diff --git a/inventory/sample/group_vars/k8s_cluster/k8s-net-calico.yml b/inventory/sample/group_vars/k8s_cluster/k8s-net-calico.yml
index a463350bb..cc0499d00 100644
--- a/inventory/sample/group_vars/k8s_cluster/k8s-net-calico.yml
+++ b/inventory/sample/group_vars/k8s_cluster/k8s-net-calico.yml
@@ -109,6 +109,10 @@ calico_pool_blocksize: 26
 # calico_ip_auto_method: "interface=eth.*"
 # calico_ip6_auto_method: "interface=eth.*"
 
+# Set FELIX_MTUIFACEPATTERN, Pattern used to discover the host’s interface for MTU auto-detection.
+# see https://projectcalico.docs.tigera.io/reference/felix/configuration
+# calico_felix_mtu_iface_pattern: "^((en|wl|ww|sl|ib)[opsx].*|(eth|wlan|wwan).*)"
+
 # Choose the iptables insert mode for Calico: "Insert" or "Append".
 # calico_felix_chaininsertmode: Insert
 
diff --git a/roles/network_plugin/calico/defaults/main.yml b/roles/network_plugin/calico/defaults/main.yml
index 2de146514..0c2be2dd8 100644
--- a/roles/network_plugin/calico/defaults/main.yml
+++ b/roles/network_plugin/calico/defaults/main.yml
@@ -108,6 +108,10 @@ calico_wireguard_repo: https://download.copr.fedorainfracloud.org/results/jdoss/
 # calico_ip_auto_method: "interface=eth.*"
 # calico_ip6_auto_method: "interface=eth.*"
 
+# Set FELIX_MTUIFACEPATTERN, Pattern used to discover the host’s interface for MTU auto-detection.
+# see https://projectcalico.docs.tigera.io/reference/felix/configuration
+# calico_felix_mtu_iface_pattern: "^((en|wl|ww|sl|ib)[opsx].*|(eth|wlan|wwan).*)"
+
 calico_baremetal_nodename: "{{ kube_override_hostname | default(inventory_hostname) }}"
 
 kube_etcd_cacert_file: ca.pem
diff --git a/roles/network_plugin/calico/templates/calico-node.yml.j2 b/roles/network_plugin/calico/templates/calico-node.yml.j2
index cc461516b..3af01c8e7 100644
--- a/roles/network_plugin/calico/templates/calico-node.yml.j2
+++ b/roles/network_plugin/calico/templates/calico-node.yml.j2
@@ -275,6 +275,10 @@ spec:
             - name: IP6_AUTODETECTION_METHOD
               value: "{{ calico_ip6_auto_method }}"
 {% endif %}
+{% if calico_felix_mtu_iface_pattern is defined %}
+            - name: FELIX_MTUIFACEPATTERN
+              value: "{{ calico_felix_mtu_iface_pattern }}"
+{% endif %}
 {% if enable_dual_stack_networks %}
             - name: IP6
               value: autodetect